Frontline Covid-19 workers, the Black Lives Matter founders and Donald Trump all feature on a list of Time magazine's 100 most influential people of 2020.
A record number of doctors, nurses and scientists have been named this year as well as the highest number of women to be included to date.
Among the Britons on the list are Fleabag's Phoebe Waller-Bridge, and Michaela Coel, the writer behind the TV series I May Destroy You.
The list features those involved in transgender, women's rights, and environmental campaigns, as well as world leaders such as China's Xi Jinping, and Germany's Angela Merkel.
Dr Anthony Fauci
The US' leading infectious disease expert has been named and praised in a tribute by late-night TV host Jimmy Kimmel for refusing "to be pressured by politicians".
He was also described as someone who delivered the truth "as difficult as it may be to hear, earnestly, and with one goal: to save lives".
The director of the National Institute for Allergy and Infectious Diseases has become a trusted voice on the pandemic.
Amy O'Sullivan
Amy O'Sullivan, a nurse in Brooklyn, made the list to represent "an army of health care workers... who risked everything to service others," wrote journalist Katie Couric.
Ms O'Sullivan treated the first COVID-19 patient at the Wyckoff Hospital, who became the city's first death in early March.
The nurse became ill and spent four days on a ventilator before recovering and was back to work less than two weeks later.
Black Lives Matter founders
Patrisse Cullors, Alicia Garza and Opal Tometi started the Black Lives Matter movement in response to the fatal shooting of Trayvon Martin in 2012.
In a tribute written by his mother Sybrina Fulton, she describes Ms Cullors, Ms Garza and Ms Tometi as only being three "but they are everywhere".
"We can't give up", she continues. "Patrisse, Alicia and Opal won't."
President Donald Trump
The 45th President of the United States, with his "norm-shattering presidency", is referred to in more scathing terms than others on the list.
Brian Bennett, TIME's senior White House correspondent, writes that Mr Trump "can bend the government, often to serve his personal political interests".
Joe Biden
Mr Trump's election rival Joe Biden is written about on the list in rather glowing terms in comparison.
"Joe Biden is honest, compassionate and empathetic - but most of all, he is a public servant," writes Jim Clyburn, a Democratic congressman.
Megan Thee Stallion
The 25-year-old has fast become one of the most influential figures in rap music.
Actress Taraji P Henson says: "Once you discover her, you become a fan... the industry might try to pigeonhole her in this rap game, but she's got a plan that's much bigger."
Megan Thee Stallion has had two UK top 10 singles this year.
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