Defending champions Asante Kotoko are chasing their fourth straight win under head coach Herbert Addo against Real Tamale United at the Tamale Park on Wednesday.RTU go into the tie heavily bruised after last Sunday's 3-0 defeat at Tema Youth.King Faisal believe they hold the advantage to hand Hearts of Oak their third straight defeat at the Baba Yara Stadium.Leaders Hearts are yet to recover from the 0-1 loss to rivals Asante Kotoko in the local derby as 11 points separate the two sides.Liberty Professionals must overhaul themselves to beat Berekum Arsenals in Dansoman and mobve away from the relegation zone.Wa All Stars will host Tema Youth and AshantiGold play All Blacks at the Len Clay Stadium.Chelsea of Bechem play Sekondi Eleven Wise at the Sunyani Coronation Park.Hasaacas are fancied for the maximum points against Kessben FC at the Sekondi Stadium.Sporting Mirren tackle Heart of Lions at the Ohene Djan Stadium.Source: ghanasoccernet.com