Serena Williams says she is "on edge" as the US tennis star revealed the impact self-isolating is having on her psychologically amid the novel coronavirus outbreak.

The 23-time grand slam winner said last week she would be entering into six weeks of "solitude" to take precautions against contracting COVID-19, only spending time with her family.

However, in a series of videos posted on her TikTok account, Williams detailed her experience so far, in particular her worries around the health of her two-year-old daughter Olympia. 

"Now I've been social distancing for actually a really long time, for probably two weeks now, and every little thing makes me crazy," Williams said.

"Any time anyone sneezes around me or coughs I get crazy.

"She (Olympia) coughed, I got angry and gave her a side-eye. I gave her that 'angry Serena' and then I got sad. I was like: 'Is she OK? Is there something wrong with my daughter? Is there anything I can do?' 

"I just don't know what to do, so instead of being relaxed I'm really under a ton of stress."Both the ATP and WTA announced this week there will be no tournaments played until June at the earliest.