At least eight people have died in the US Midwest as the region shivers in the grip of its worst cold snap in decades.
An Iowa student found dead outside a college building is among the victims of the deadly freeze.
Hospitals have been treating patients reporting frostbite as life across a swathe of the nation grinds to a halt.
The iciest blasts may still come on Thursday. Ninety million people - a third of the US - have seen temperatures of -17C (0F) or below.
Some 250 million Americans overall have experienced the "polar vortex" conditions, but southern states such as Florida have escaped the brutal chill.
How did the fatalities occur?
- University of Iowa student Gerald Belz, 18, was found unresponsive behind a campus building before dawn on Wednesday and later died in hospital. Officials said weather was a factor. His father told local news channel KCRG that Gerald was a "mama's boy with a tough exterior".
- A 70-year-old man in Detroit, Michigan, was found dead in front of a neighbour's home on Wednesday
- Another Michigan man in his 70s was found frozen to death in his neighbourhood. Officials said he was "inadequately dressed for the weather" and was probably disoriented
- On Tuesday, 55-year-old Charley Lampley froze to death in a garage in Milwaukee, Wisconsin, having "apparently collapsed after shovelling snow", according to a medical examiner
- An 82-year-old man in Pekin, Illinois, died from hypothermia after apparently falling outside his home on Tuesday
- A 75-year-old man was fatally struck by a snow plough near Chicago on Monday. The driver has since been placed on paid leave pending an investigation, according to WGN9 News
- In northern Indiana, a young couple died after a collision on icy roads
What's the forecast?
Thursday could see America's third largest city of Chicago breaking its 1985 record low of -32C (-25F), according to meteorologists. The city has already passed the record low for 31 January.
The National Weather Service (NWS) announced Rockford, Illinois, west of Chicago, broke its all-time low record of -32C (-27F) when temperatures dipped to -34C (-30F) on Thursday morning.
Cities across Iowa have also broken temperature records.
Cotton, Minnesota, was the coldest place in the US on Thursday, however, with a low of -48C (-56F) based on preliminary data.
The chill is drifting eastward on Thursday, bringing sub-zero temperatures to north-eastern cities such as Boston.
Areas downwind of the Great Lakes are expected to be buried by intense "snow lakes" into Thursday night.
The region near Buffalo, New York, should see the heaviest snowfall. Snow could fall at rates of 3in-5in (7cm-12cm) per hour.
The icy cold is expected to loosen its grip on Friday.
With wind chill factored in, the Midwest and Great Lakes have felt temperatures closer to -40C (-40F) and -53C (-63F), which is enough to cause frostbite in under five minutes.
But by the end of the weekend, Chicago could see temperatures as high as 10C (50F).
"It's going to be at least a 60-degree swing for Chicago," David Hamrick, a National Weather Service forecaster, told Reuters news agency.
How is the cold snap affecting daily life?
The Arctic weather could cost the US billions of dollars. In 2014, a similar polar freeze cost the country an estimated $5bn (£3.8bn), CBS News reported.
In Minnesota, residents have been asked by natural gas company Xcel Energy to reduce their home thermostats to 17C (63F) in order to help the company handle heating demands.
Michigan residents have had similar requests from their utility companies as providers struggle to keep the states warm.
Native American tribes in the northern Midwest states have been helping their members obtain heating supplies during the chill as many live in poor-quality housing, the Associated Press reported.
Detroit has had more than two dozen water mains freeze over this week. A city spokesman told the Associated Press the pipes were installed up to 1.8m below the frost line, but with such drastically low temperatures, the ground has still frozen through.
The US Postal Service has suspended all mail deliveries for the second day to parts of six states.
More than 2,300 flights have been cancelled and another 3,500 delayed due to the polar vortex.
As ice and snow continue to build up, roads have become increasingly dangerous across the northern US. In Illinois, police said they had assisted more than 1,300 motorists and received 460 calls in eight hours - 10 times the norm.
One woman in the state was caught speeding at 115mph (185km/h) on a snowy road with a 35mph (56km/h) speed limit.
At least two people were critically injured in a 27-car pile-up on icy roads in Wyomissing, Pennsylvania.
Twenty-one vehicles, including a lorry, were involved in a pile-up in Buffalo, New York, during a snowstorm on Wednesday. Officials have not released details on any injuries, WKBW News reported.
It is reported that the lorry should not have been on the road at the time, due to a weather-related ban.
In Minnesota, prison visits were cancelled over the cold, according to the New York Times.
How cold is Chicago?
The Illinois city became a frozen ghost town after temperatures fell to -30C (-22F), colder than parts of Antarctica.
A Good Samaritan paid for 70 homeless Chicagoans to stay in a hotel as temperatures dropped.
Salvation Army spokeswoman Jacqueline Rachev told the Washington Post: "It's a deadly situation for anyone. We're thrilled that someone was in a position to be able to do this."
Most of the thousands of cancelled flights this week were coming out of Chicago's airports - O'Hare International is ranked as one of the top 10 busiest airports in the world.
Amtrak also cancelled all trains into Chicago on Wednesday, affecting 55 trains, and said most would be cancelled on Thursday as well.
As the Midwestern city is one of the company's hubs, train services nationwide could be impacted.
The chill was even too much for Chicago's Disney on Ice show, which cancelled its Wednesday performance.
More than 600 local schools have shut, keeping 360,000 students at home.
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