Audio By Carbonatix
Levels of positive tests are rising in London and could be on the up in the East of England, according to data from the Office for National Statistics.
Figures for the week to 5 December, as England's second lockdown was ending, suggest infection levels continued to fall in other regions.
Infection rates are still highest in children of secondary school age, the ONS says.
Across the UK, the picture is mixed, with Wales seeing rising infections.
In Northern Ireland, the percentage of people testing positive continues to fall - while in Scotland it has stayed the same.
The R number - or reproduction number - of the virus is now between 0.9 and 1.0 for the UK - slightly up from 0.8-1.0 last week. But in some regions in the south and east it could be above 1, indicating infections are likely to be growing there.
The ONS figures are one source of data used by the government's scientific advisers to judge the spread of the virus, and take decisions on restrictions on people's daily lives.
They are based on swab tests of thousands of people in households, whether they have symptoms or not. The estimates are thought to give a more accurate picture of how many people are infected with the virus than data on positive tests alone.

Infection levels in London started to rise sharply before the end of lockdown, according to the ONS, after falling in late November.
In all other regions, including the North West and North East, and Yorkshire and the Humber, the percentage of people testing positive is decreasing.
But there are "early signs" rates may be increasing in the east of England, the ONS says.
It estimates:
- one in 115 people have the virus in England
- one in 120 in Scotland
- one in 120 in Wales
- one in 235 in Northern Ireland
Data on cases - or confirmed positive tests, from Public Health England - also suggests the epidemic is growing in parts of London and the south-east of England.
Areas such as Basildon, Medway and Havering are now experiencing more than 400 cases per 100,000 people.
England's tiers system is due to be reviewed on 16 December and there have been suggestions that London should be moved from tier two to tier three to avoid a spike in deaths over Christmas.
Kent is already in tier three while Essex is in tier two.

Latest Stories
-
NPA pushes back on proposals to scrap Fuel Price Floor Policy
16 minutes -
Policy stability, currency strength and regulatory reforms key to attracting investors – Stanbic Bank
54 minutes -
Stanbic Bank Ghana begins 2026 with thanksgiving service; reaffirms support for Ghana’s economic recovery
1 hour -
Nigerian imam honoured for saving Christian lives dies aged 90
1 hour -
What a seventh term for 81-year-old leader means for Uganda
1 hour -
AFCON: ‘Shameful’ and ‘terrible look’ – the chaos that marred Senegal’s triumph
2 hours -
Rashford scores but Barca lose to 10-man Sociedad
2 hours -
Diaz will ‘have nightmares’ over ‘Panenka’ failure
2 hours -
Tragic death of Chimamanda Adichie’s young son pushes Nigeria to act on health sector failings
2 hours -
‘I want to show the world what Africa is’: YouTube star brings joy and tears on tour
2 hours -
‘An ambassador for African football’ – Mane is Senegal’s Afcon hero
3 hours -
‘Europe won’t be blackmailed,’ Danish PM says in wake of Trump Greenland threats
5 hours -
Three admit £70m tree planting pension fraud in UK
5 hours -
How crypto criminals stole $700m from people – often using age-old tricks
5 hours -
Construction emissions pose rising climate risk, Scientists Say
5 hours
