Every society trivet on knowledge and information; education has proven to provide that incentives for building an informed and knowledge based human resource in our country and the world in general; Nelson Mandela once said, “education is the most powerful weapon which you can use to change the world’ it is therefore important for every individual to acquire quality education to stay relevant within the tenets of today’s global village. Ghana as a lower income country has experienced exponential development in the educational sector creating room for various groups and organizations to establish universities and colleges, the liberalization of Ghana’s educational sector since the return to constitutional governance has served as a stimulus for human, industrial and technological colleges or institutions to spring up. This development has given students myriad of options to select from which universities or colleges they want to attend to acquire the relevant skills and knowledge for development. However, the compelling issues that linger in the minds of every individual are how well such Institutions maintain quality assurance in the various colleges and tertiary institutions? Additionally, how well are we assured that all the various private institutions or colleges are accredited by the National Accreditation Board (NAB). Accreditation is the means of protecting the interests of students, parents, stakeholders and indeed the general public in tertiary education. There have been instances were institutions like the Makessim based University of Jesus Christ of Nazareth and the Ideas University in Fiapra, Brong Ahafo had serious challenges with the National Accreditation Board for not meeting the standards required. Some students also recently took their Institutions and NAB to court for their withdrawal because they did not enter the University or their colleges with the required grade. The National Accreditation Board was established with the enactment of PNDC law 317 of the NAB Law 1993 (PNDC. 317), this law has since been replaced by Act 744 of 2007. According to the National Accreditation Board all public and private institutions are required to seek accreditation and their mandate is to ensure that tertiary educational institutions have the physical, material, financial and human education. It is also the mandate of NAB to ensure quality assurance: assuring thresholds quality in higher education, and quality improvement thus assuring that institutions and programmes have processes to try to do what they do better. The board’s vision is to ensure high standards in Tertiary Education and seeks to establish and advance the international comparability of Ghana’s tertiary education system by ensuring the development of high quality institutions. Facts available to the National Accreditation Board indicate that there are some colleges and tertiary institutions in Ghana which are not accredited and run unaccredited programmes; most importantly, most institutions which manage to get their accreditation are fail to meet the required standards demanded by law in assuring quality education. It is captivating to note that, most private universities and colleges are market driven: (thinking of how to make profit at the detriment of maintaining good quality assurance). The accreditation board is also concerned about the high level of degree milling by institutions, a situation where fake certificates are awarded to students, as a result of this vice practices, students who by shear ignorance enroll in unaccredited colleges or tertiary institutions end up with certificates that are not recognized by the job market and industry both nationally and internationally. Recent report by the Association of Ghana Industry and also the Ghana Employers Association indicates that most students who graduate from the various tertiary institution or colleges largely do not meet their standards and expectations, such worrying trend also contribute to the high level of unemployment in the country. The call for tertiary institutional integrity must be a collective effort from all stakeholders including the state. There must be a shift from the centralized system of maintaining quality assurance to that of a decentralized system to enhance the effectiveness of the law. The Ministry of Education must also adequately resource the National Accreditation Board to carry out its duties effectively, especially in the monitoring of cross border tertiary education and distance learning programmes that award degree and other professional certificates. Students must also ensure that they enquire from the National Accreditation Board, to check the validity of courses and programmes of any tertiary institution in Ghana before enrolment, to avoid investing in futility. Finally, the tertiary institutions or colleges must subject itself to the scrutiny of quality assurance and standards by self-appraisal and assessments; this I believe will go a long way to establish their institution as a credible one devoid of any accreditation challenges.