Hundreds of residents living in Peace Town in Amanfro in the Ga South Municipality have been cut off from the rest of the capital after several hours of rain on Saturday and Sunday.
Some of the affected communities are Nurses Quarters, Tomefa, Abeam University of Technology and Azuma Farms.
So far, only heavy-duty vehicles are able to cross.
On Monday morning, children could not go to school because their parents are not willing to risk the receding waters.
The road now turned water-way is disposed to snakes and other dangerous wild animals which threaten the safety of children and other vulnerable community members.
Residents say authorities have not been sensitive to their plight since the problem has been with them for many years.