Audio By Carbonatix
A tiny "genetic patch" can be used to prevent a form of deafness which runs in families, according to animal tests.
Patients with Usher syndrome have defective sections of their genetic code which cause problems with hearing, sight and balance.
A study, published in the journal Nature Medicine, showed the same defects could be corrected in mice to restore some hearing.
Experts said it was an "encouraging" start.
There are many types of Usher syndrome tied to different errors in a patient's DNA - the blueprint for building every component of the body.
One of those mutations runs in families descended from French settlers in North America.
When they try to build a protein called harmonin, which is needed to form the tiny hairs in the ear that detect sound, they do not finish the job.
It results in hearing loss at birth and has a similar effect in the eye where it causes a gradual loss of vision.
Patch
Scientists at the Rosalind Franklin University of Medicine and Science, in Chicago in the US, designed a small strip of genetic material which attaches to the mutation and keeps the body's factories building the protein.
When mice with Usher syndrome were injected with the "genetic patch" they grew up able to hear and had no balance problems.
For the first couple of months their hearing was close to normal in the lower frequencies, but had started to deteriorate by six months.
One of the researchers Michelle Hastings, assistant professor at Rosalind Franklin University, told the BBC: "It was a surprising result that we could treat mice right after they are born and have such a profound effect."
The treatment had to be given early, within the first 10 to 13 days of life.
The researchers do not know if this is because the patch needs to be in place during early development in order to make a difference or if the patch struggles to make it into the inner ear beyond a certain point.
This could raise problems in designing a similar treatment in people. Humans spend far longer in the womb than mice meaning any treatment might need to be given before a baby is born.
Dr Ralph Holme, head of biomedical research at Action on Hearing Loss, said: "It is encouraging that researchers have been able to rescue hearing using an approach which targeted a specific type of inherited deafness.
"More research is now needed to understand how this new therapy could be used to treat this particular type of Usher Syndrome in humans and discover whether vision can also be rescued."
DISCLAIMER: The Views, Comments, Opinions, Contributions and Statements made by Readers and Contributors on this platform do not necessarily represent the views or policy of Multimedia Group Limited.
Tags:
DISCLAIMER: The Views, Comments, Opinions, Contributions and Statements made by Readers and Contributors on this platform do not necessarily represent the views or policy of Multimedia Group Limited.
Latest Stories
-
Ghana’s programme performance has been broadly satisfactory – IMF Board
7 minutes -
Former chancellor George Osborne joins OpenAI
16 minutes -
No bank has been cited, sanctioned by any regulatory or law enforcement agencies – Association of Banks
21 minutes -
Ghana’s GH₵10m relief support to Jamaica grounded in compassion and solidarity – Ablakwa
24 minutes -
Speaker, Ga Mantse to headline GJA Dinner Night
31 minutes -
JoyNews to host National Dialogue on declining adherence to standards on Thursday
34 minutes -
Newmont to fully fund 13 kilometers Ntotroso–Kenyasi road in 2026
44 minutes -
Lands Ministry engages Ewoyaa chiefs, residents in successful lithium agreement talks
53 minutes -
Cirque De Soir opens in Accra, adds sparkle to festive season
1 hour -
Adom Kiki wins Worship Artiste of the Year at 4th Praise Achievement Awards
1 hour -
Economic Fighters League urges inclusion as Constitutional Review Report nears completion
1 hour -
Walewale NPP delegates show love to Bawumia, refuse to let him “waste time” campaigning
2 hours -
GhIE urges engineers to uphold competence and due process in national infrastructure delivery
2 hours -
Mahama directs upgrade of Ho and Hohoe from Municipal to Metropolitan status
2 hours -
Netherlands donates new scanners to boost Ghana’s fight against drug trafficking
2 hours
