Audio By Carbonatix
An artificial pancreas given to pregnant women with diabetes could save mothers' lives and improve the health of their babies, researchers say.
Hormonal changes during pregnancy coupled with diabetes make regulating sugar levels difficult, which can have damaging consequences.
The Diabetes Care research shows an artificial pancreas can keep sugar at normal levels.
Diabetes UK, which funded the work, said it could make pregnancy safer.
Pregnancy worries
People with Type 1 diabetes are unable to control their blood sugar levels because their pancreas stops producing insulin.
It is a fatal condition which can be controlled by regular insulin injections, but that becomes much more complicated during pregnancy.
The safe range for blood sugar levels is much narrower then, and high or low levels which would be fine for an adult can damage a baby.
Dr Helen Murphy, from Cambridge University, told the BBC: "Half of all babies born to mothers with Type 1 diabetes are overweight or obese at birth because of too much sugar in the blood".
An earlier study of pregnant women in England, Wales and Northern Ireland showed the rate of stillbirths and deaths in the first week was four times greater in women with Type 1 diabetes, affecting 32 out of every 1,000 pregnancies.
Pregnancy can also be dangerous for the mother, who can end up with lower blood sugar levels and sometimes lose the warning signs for potentially fatal hypoglycaemic attacks.
During pregnancy, women with Type 1 diabetes spend 10 hours every day with sugar levels outside those recommended.
Artificial Pancreas
Researchers at the Medical Research Laboratories in Cambridge fitted artificial pancreases to 10 women with the disease.
A sensor continually monitored sugar levels, which fed the information to a computer, which then told an insulin pump how much of the hormone to inject.
The early study showed that normal sugar levels could be maintained.
Dr Helen Murphy, from Cambridge University, said: "For women with Type 1 diabetes, self-management is particularly challenging during pregnancy due to physiological and hormonal changes.
"These high blood glucose levels increase the risk of congenital malformation, stillbirth, neonatal death, preterm delivery, macrosomia [oversized babies] and neonatal admission. So to discover an artificial pancreas can help maintain near-normal glucose levels in these women is very promising".
However she said it would probably require care before pregnancy to reduce the number of stillbirths and neonatal deaths.
Dr Iain Frame, director of research at Diabetes UK, said: "Although early days, this exciting area of research, funded by our donors, has huge potential to make pregnancy much safer for women with Type 1 diabetes, and their babies.
"We now need to see an extension of this study, one which tests larger numbers of women, and then take it out of the hospital and into the home."
The researchers say they have proved the concept works and hope to begin trials in the home later this year.
DISCLAIMER: The Views, Comments, Opinions, Contributions and Statements made by Readers and Contributors on this platform do not necessarily represent the views or policy of Multimedia Group Limited.
Tags:
DISCLAIMER: The Views, Comments, Opinions, Contributions and Statements made by Readers and Contributors on this platform do not necessarily represent the views or policy of Multimedia Group Limited.
Latest Stories
-
Dr Agyemang rejects Health Committee Chairman’s ‘resign’ comment, calls it unfortunate
6 minutes -
‘No bed syndrome’: GMA calls for National Emergency Healthcare Policy
6 minutes -
“Telling tired health workers to resign isn’t the solution”
7 minutes -
Ghana Meteo sends urgent alert over thunderstorm heading from Togo, Benin
11 minutes -
How my daughter’s father infected her with HIV – Woman breaks down
15 minutes -
Health Ministry targets 30% reduction in maternal deaths within two years
22 minutes -
VCIC’s Francis Senanu Dekutse commends gov’t agricultural drive as 500 bags of fertiliser reach Keta farmers
24 minutes -
VCIC’s Francis Senanu Dekutse champions women in agriculture with 500 bags of fertiliser distribution in Keta
24 minutes -
Anthony Woode draws industry praise after Sonia Uche’s endorsement
29 minutes -
Court denies businessman accused of allegedly beating his girlfriend to death bail
47 minutes -
Amin Adam commissions 12-unit classroom block at former school NOBISCO
55 minutes -
We must build infrastructure, not just policy papers – Matilda Asante-Asiedu
56 minutes -
COCOBOD signals new funding model for 2026/27 cocoa season at 2026 ACFIF Conference
1 hour -
Early UK local election results point to big losses for Starmer’s Labour Party
1 hour -
I authorised OSP to prosecute cases – Former AG Godfred Dame
2 hours