It's the big one!
José Mourinho is well equipped to exploit Liverpool’s weaknesses with the power, organisation and counter-attacking style of his joint league leaders.
But that would require a different strategy to what he successfully employed at Anfield last season. Marouane Fellaini and Paul Pogba are big misses for Manchester United but Sadio Mané’s absence will be felt by Jürgen Klopp, too.
Liverpool’s performances have not been as bad as recent results indicate but they can ill-afford to fall 10 points behind their arch rivals so early in the season. Both sides have opportunity to deliver a statement of intent.
Do you agree with Gary and Nii on Liverpool v Man Utd? Can you do better? Then predict here now!
Meanwhile, the rest of the nine EPL games are all analysed and predicted here! Check 'em out.