Premier League clubs continue jostling for positions on a busy midweek of international football action across the world.Six matches will be played on Wednesday with the remaining two coming off 24 hours later in the Glo Premier League.With a six-point lead to their credit, Asante Kotoko will be attempting to preserve their place at the summit of the standings with a game against Aduana Stars at the Agyemang-Badu Park coming up on Wednesday.A last-gasp goal condemned Aduana to defeat in Wa but as they return home, the former champions will be determined to claim all three points against the Porcupine Warriors.Hearts of Oak are ruing their failure to beat Bechem Utd at home but must now pick up the pieces for their travel to the Len Clay Stadium where they played AshantiGold.Two successive defeats have resulted in Berekum Chelsea falling off the pace with a ten-point gap separating them from the top.The champions will be looking for home comforts when they welcome Wa All Stars to the Golden City Park as they chase their first win in the second round.Liberty Professionals, still smarting from their defeat to Kotoko return to the Car Reindorf Park to take on Ebusua Dwarfs.New Edubiase will be missing the league's top-scorer Emmanuel Baffour as they travel to Sekondi to face a struggling Medeama side.Medeama have a rather poor record till date in the league. After huge spending, the Tarkwa side have won seven games and lost ten times with no draw and they are yet to justify the cash splashed before the season kicked off.Tema Youth entertain bottom club, Wassaman at the Tema Park to round up the midweek fixtures.On Thursday, Heart of Lions, who claimed a point off Mighty Jets on Monday will host Berekum Arsenal at the Kpando Park.In Bechem, home team, Bechem United take on Mighty Jets.