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Sadio Mane will play no part in the 2022 FIFA World Cup for Senegal after coming off injured in Bayern Munich's league game on Tuesday, November 8.
Mane went down on 15 minutes and had to be replaced by Leroy Sane.
It comes just 13 days before Mane's Senegal play their first game at the 2022 World Cup against the Netherlands.
"He'll have to have an X-ray to see what's happened," said Bayern coach Julian Nagelsmann.
"He took a blow to his tibial plateau [the head of the shin]. It's a painful spot."
Bayern, meanwhile, cruised to victory with Serge Gnabry scoring a hat-trick.
However, French newspaper, L'Equipe reports the Senegal starman will not be available for the Mundial to be staged in Qatar.
The former Liverpool player is reported to be suffering from a tendon and is expected to miss several weeks of competition.
Senegal coach Aliou Cissé is due to announce his list of players who will go to Qatar on Friday.
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