Medeama continued their good form after a convincing 3-0 victory against Ebusua Dwarfs.
The Mauve and Yellows took the lead through Ahmed Toure in the second half.
Ibrahim Yaro doubled their lead before Prince Opoku Agyemang wrapped up the victory with a cheeky back heel finish.
The win extends Medeama’s win run to four games now as they return to the summit of the table.
Hearts of Oak had an afternoon to forget at Dawu losing 2-0 to Dreams FC.
Second half goals from Ali Huzaf and Sylvester Simba was enough to beat Hearts.
The Phobians were reduced to 10 men after Nuru Sulley was sent off after picking up two yellow cards.
Samuel Boadu’s men are now winless in two games and have dropped to fifth in the table.
Inter Allies’ hope of survival was further dented by Bechem United.
The Hunters raced into a two goal lead in the first half through Moro Salifu and Hafiz Konkoni.
Hashmin Musah pulled one back for the Eleven is to One boys as the game finished 2-1.
Inter Allies are now eight points from safety with 12 games to go.
Elmina Sharks won their fourth consecutive home game defeating AshGold 2-1.
The Miners took the lead through David Abagna but two quick fire second goals from Ismael Hammond and Kingsley Braye secured the victory for Sharks.
Great Olympics returned to winning ways beating Liberty Professionals 2-0 at the Accra Sports stadium.
Annor Walker’s side were winless in their previous three games and needed goals from Maxwell Quaye and Joshua Rhule to end that poor run.
The result also ended Liberty’s streak of three straight victories.
Karela’s poor form continued as they salvaged a 1-1 draw against King Faisal.
The Aiyinase-based side are still without a win in the second round and have fallen from the title race.
Zubairu Ibrahim had given King Faisal the lead in the first half.
A late goal from Maxwell Boakye saved Karela as they ended up with a point stretching their winless run to six games.
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