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All the team news ahead of the weekend with Sergio Aguero back for Manchester City but Vincent Kompany and David Silva are out for the visit of Liverpool.
SATURDAY (all kick-offs 3pm UK time unless stated)
Watford v Manchester United (12:45pm)
Watford striker Odion Ighalo faces a late fitness test before manager Quique Sanchez Flores selects his team. Louis van Gaal is suffering from a striker shortage. Wayne Rooney (illness) and Anthony Martial (foot) are out while James Wilson cannot play 90 minutes because of a lack match fitness.
Swansea v Bournmouth
Swansea manager Garry Monk has a fully-fit squad to choose from. Bournemouth manager Eddie Howe has a decision to make up front as Glenn Murray returns from injury in time to be selected.
Southampton v Stoke City
Southampton defender Virgil van Dijk should be fit to face Stoke despite suffering a knee injury on international duty with Holland. West Bromwich Albion v Arsenal Gareth McAuley is suspended for West Brom. James Chester and Jonas Olsson are in line to replace him with Chester struggling to break into the Baggies side since his £8million summer move from Hull. Laurent Koscielny and Olivier Giroud's readiness to play for Arsenal will be assessed by Arsene Wenger.
Chelsea v Norwich City
Chelsea are again without Thibaut Courtois and Radamel Falcao. Norwich expect winger Nathan Redmond to shake off a thigh injury. Newcastle United v Leicester City Leicester striker Jamie Vardy will be assessed as he chases a record-equalling goal at Newcastle.
Everton v Aston Villa
Everton midfielder Tom Cleverley is poised to return to action, while a late decision will be made on whether Leighton Baines is ready for his maiden first-team appearance of the season. Jordan Amavi has been ruled out for the rest of Aston Villa's season with a serious knee injury he suffered on international duty with France's Under 21s. \
Manchester City v Liverpool
Sergio Aguero hopes to return for City. The home side are without captain Vincent Kompany due to his hamstring problems while David SIlva misses out with an ankle injury. Liverpool manager Jurgen Klopp will make a late decision on whether to include striker Daniel Sturridge.
SUNDAY
Tottenham Hotspur v West Ham United (4pm)
Tottenham winger Andros Townsend has returned to the first-team squad. Midfielder Alex Song is set to make his first appearance of the season after returning to training.
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