Real Madrid forward Isco has been diagnosed with acute appendicitis and is set to have an operation, the club have announced.

The Spain international scored the opening goal in Real's 3-0 win over Roma in the Champions League last week.

Isco, 26, has played six times this season but will not be available for upcoming games, including a La Liga clash with Sevilla on Wednesday.

Real's statement did not put a timeframe on the player's recovery.