JP Morgan is set to take over the troubled US bank First Republic in a deal brokered by regulators.
The Federal Deposit Insurance Corporation (FDIC) confirmed in a statement that First Republic had collapsed on Monday.
Investment banking giant JP Morgan will now take on "all of the deposits and substantially all of the assets of First Republic Bank".
First Republic becomes the third major US bank to collapse in recent months.
The San Francisco-based lender's shares fell by more than 75% last week after it revealed that customers had withdrawn $100bn (£79.6bn) of deposits in March.
It follows on from the collapse of Silicon Valley Bank (SVB) in March, which prompted fears of a wider banking crisis.
That was swiftly followed by the demise of another US lender, Signature Bank.
A deposit flight from US lenders has forced the Federal Reserve, the US central bank, to step in with emergency measures to stabilise financial markets.
In March, a group of 11 US banks stepped forward to pump $30bn into First Republic in a bid to stabilise the business, but the efforts proved futile.
Founded in 1985, First Republic is a mid-sized US lender, similar to SVB. For years, it has lured wealthy clients - whose money was at risk before the takeover was announced after a weekend of negotiations.
The terms of First Republic's acquisition by JP Morgan are not yet known.
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