Award-winning actress Lupita Nyong’o has revealed that a uterine fibroid condition first diagnosed in 2014 has returned and is now far more serious than before.

Speaking on ‘Today’, she said doctors told her she now has more than 50 fibroids, the largest the size of an orange, and that her only options are invasive surgery or living with ongoing pain.

Nyong’o said she first had fibroids removed in 2014, when surgeons took out 23 growths. She described the current diagnosis as a shock and a source of real fear about her reproductive health.

She told viewers she is not yet ready to undergo another myomectomy, a procedure that removes fibroids while trying to preserve the uterus, because of how invasive it can be and the risks involved.

Beyond describing her symptoms and treatment dilemma, Lupita Nyong'o has shifted the conversation toward advocacy.

She is fundraising for research into less invasive and non-invasive treatments and has been working with groups focused on uterine health to push for better options and awareness.

Speaking openly, she said sharing her story helped her move past shame and find community among other women facing the same condition.

Medical experts say uterine fibroids are common and can cause heavy bleeding, prolonged periods, pelvic pain and other disruptive symptoms.

For many people, the choice between surgery and conservative management depends on fibroid size, location, symptoms and fertility goals.

Lupita Nyong’o’s disclosure has drawn renewed attention to a broader issue: the need for more research and clearer guidance for fibroid patients.

She has called for more conversation and better science so that people facing fibroids can access effective, less risky treatments without stigma.