Thousands of workers across the country are massing up at designated points to protest what they say is the worsening economic situation.
The workers on Wednesday rejected an appeal from government to hold on to the demonstration as efforts were being made to address their concerns.
The one-day action is being held simultaneously in all ten regions with Accra expected to record the highest turnout of discontented workers from all sectors of the economy.
Workers in both formal and informal sectors, including commercial transport operators and shop owners have joined in the march, to register their frustration at government's failure to take action on the economy.
At the Obra Spot at the Kwame Nkrumah Circle here in Accra, Joy News' Beatrice Adu reports over 500 persons clad in red and black, had reported to take part in the protest march.
They will march through the streets from Adabraka, Trust Towers, TUC area, National Theatre and finally to Hearts Park, where a petition will be presented to the Minister of Employment and Labour Relations Haruna Iddrisu.
Beatrice said about 500 heavily armed personnel from the police service had taken position to ensure the demonstration goes on peacefully.
Meanwhile, General Secretary of the Industrial and Commercial Workers Union (ICU), Solomon Kotei has told Joy FM that the protest is not demand wage increases but to mount pressure on government to to introduce measures that will turn the economy around.
"We are not talking about wages at all in this struggle…we have spoken about the ability [of government] to halt the depreciation of the cedi against the major trading currencies, review prices of petroelum products in a way that continuous price increments that is affecting the economy will be minimised," Mr. Kotei said on the Super Morning Show, Thursday.