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Manchester City midfielder Yaya Toure, Swansea striker Wilfried Bony and West Ham top scorer Diafra Sakho are among the Premier League players who may miss club games in the new year to compete in the Africa Cup of Nations.
The final six nations to qualify were confirmed on Wednesday.
Newcastle and West Ham could lose three players each during the tournament between 17 January and 8 February 2015.
Equatorial Guinea are the hosts following Morocco's withdrawal.
Morocco had expressed fears an influx of foreign fans could help spread the Ebola epidemic, which has mainly affected the West African countries of Sierra Leone, Liberia and Guinea.
Reigning Afcon champions Nigeria will not defend their crown, having failed to qualify for the finals.
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