Manchester United's owners, the Glazer family, say they are considering selling the club as they "explore strategic alternatives".
The Americans bought the Old Trafford outfit for £790m ($1.34bn) in 2005.
It comes after years of protest from fans against their ownership.
A statement said the board will "consider all strategic alternatives, including new investment into the club, a sale, or other transactions involving the company."
In 2012, the Glazers sold 10% of their holding via a stock listing and have sold further shares in the following years.
"As we seek to continue building on the club's history of success, the board has authorised a thorough evaluation of strategic alternatives," said executive co-chairmen and directors Avram Glazer and Joel Glazer.
"We will evaluate all options to ensure that we best serve our fans and that Manchester United maximizes the significant growth opportunities available to the club today and in the future.
"Throughout this process we will remain fully focused on serving the best interests of our fans, shareholders, and various stakeholders."
United, who are fifth in the Premier League, have not won the title since 2013 and have not won a trophy since claiming the Europa League and EFL Cup in 2017.
There have been multiple protests against the Glazers' ownership in recent years, including one in May 2021 which caused United's home league match against Liverpool to be postponed.
Thousands of supporters marched to Old Trafford in protest before the same fixture this season, in August.
United were part of the failed European Super League project which rapidly collapsed in April 2021. Manchester United co-chairman Joel Glazer later apologised for the unrest caused.
He has since attended Fans' Forums in the wake of the supporter unrest and pledged to make shares available to fans.
Portugal captain Cristiano Ronaldo, who left Manchester United with immediate effect on Tuesday, criticised the club ownership in a controversial interview last week saying the Glazer family, "don't care about the club" on the sporting side.
The move to sell United comes amid Liverpool chairman Tom Werner saying Fenway Sports Group were "exploring a sale" of the Anfield club.
A Bloomberg report in August 2022 said that the Glazer family were willing to sell a minority stake in the club.
British billionaire Sir Jim Ratcliffe said he would be interested in buying the club before he stated in October that the Glazer family had told him they did not want to sell.
In May, a consortium led by American investor Todd Boehly and private equity firm Clearlake Capital bought Chelsea for £4.25bn.
Latest Stories
-
Access Bank Ghana Plc records commendable financial growth in quarter one, 2024
44 mins -
GFA DC charges Bashir Hayford over alleged misconduct in Bechem Utd game
52 mins -
MTN FA Cup: Dreams FC beat Soccer Intellectuals to make semis
2 hours -
Ayorkor Botchwey champions transformative investment, trade agenda
2 hours -
KNUST, University of Rwanda share experiences in implementation of Mastercard Foundation Scholars Program
3 hours -
Top 10 most visited tourist sites in Ghana 2023
3 hours -
Cecilia Dapaah case: I will reopen investigation into alleged acts of corruption – Mahama
3 hours -
GRA boss charges customs officers to be professional ahead of 2024 general elections
3 hours -
NPP thanks stakeholders for successful Ejisu by-election
3 hours -
Bawumia promises to involve chiefs in licensing miners if elected President
3 hours -
Koda should have visited the pastor to avert the prophecy – Ajagurajah
4 hours -
Emotional support alligator taken and released in swamp
4 hours -
A mate is a mate, Bawumia can’t be in the driver’s seat – NDC Communicator
4 hours -
Over 400 million Google accounts have used passkeys, but our passwordless future remains elusive
4 hours -
Kwame Nkrumah Memorial Park surpasses Aburi Gardens as most visited site in 2023 – GTA
4 hours