The Ghana Premier League matchday 24 fixture between Asante Kotoko and Hearts of Oak will be the talking point of the weekend, with the Super Clash returning to Kumasi for the first time in four years.
A win for the Porcupine Warriors will edge them closer to winning their first league title since the 2013/14 season, while Hearts are looking to close the gap between themselves and the archrivals.
Earlier before the Super Clash, Accra Lions will welcome Karela United to the Accra Sports Stadium on Saturday as they seek a return to winning ways.
AshantiGold and WAFA will go head-to-head at the Len Clay stadium while Bechem United will also battle it out with Bibiani Gold Stars for the maximum points at the Nana Fosu Gyeabour Park. Bechem are one of three clubs that are yet to lose at home in the Premier League this season.
Elsewhere in Berekum, Legon Cities will pay a friendly visit to Berekum Chelsea. Both sides are separated by just three points on the league table.
Dreams FC take on Eleven Wonders with Elmina Sharks also engaging King Faisal at home. While Sharks are unlikely to avoid the drop this season, King Faisal are currently on a five-game losing streak in the top flight.
Accra Great Olympics take on third-place Aduana Stars. After winning their last game, Real Tamale United will hope to stay on a winning note when they travel to play Medeama in Tarkwa.
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