Audio By Carbonatix
Lisa Pisano, the first person to receive a mechanical heart pump as well as a gene-edited pig kidney, died Sunday, according to NYU Langone Health, where she had the surgery.
Pisano received the transplant on April 12, but the organ failed due to limited blood flow and was removed May 29.
Her case was the first reported organ transplant in a person with a mechanical heart pump, NYU Langone said, the second known transplant of a gene-edited pig kidney into a living recipient and the first transplanted along with the animal’s thymus gland.
Pisano was brave and altruistic, Dr. Robert Montgomery, director of the NYU Langone Transplant Institute, said in a statement Tuesday.
She had said during a news conference after the procedure that even if the organ transplant didn’t work for her, it might for the next person.
“At least somebody is going to benefit from it,” she said.
Montgomery said Tuesday that “Lisa’s contributions to medicine, surgery, and xenotransplantation cannot be overstated. … Lisa helped bring us closer to realizing a future where someone does not have to die for another person to live.”
Read also: Man who received first pig kidney transplant dies
Every eight minutes, another person is added to the transplant waiting list, and 17 people from this list die each day waiting for an organ, according to the Organ Procurement and Transplantation Network. Xenotransplantation, which involves using organs from other species, is a potential solution to the shortage of available donor organs, experts say.
Doctors in the US perform xenotransplants in rare cases, with permission from the US Food and Drug Administration. For Pisano, the permission came through the agency’s expanded-access or “compassionate use” policy, which allows terminally ill patients who have no other treatment options to access experimental medical products.
Due to Pisano’s heart failure and end-stage kidney disease that required routine dialysis, she couldn’t have a standard transplant, NYU Langone said in a news release.
Before the xenotransplant, Pisano said, she had “tried everything else” and, with the surgery, was hoping to spend time with her grandkids and play with them.
The pig kidney she received was genetically altered to evade human antibodies, which typically detect and attack foreign organs. The pig’s thymus gland, which plays a role in immunity, was placed beneath the pig kidney’s cover to further help Pisano’s body accept the organ.
However, the kidney was removed in May after it was determined that it was “no longer contributing enough to justify continuing the immunosuppression regimen,” Montgomery said at the time.
Pisano’s “bravery gave hope to thousands of people living with end-stage kidney or heart failure who could soon benefit from an alternative supply of organs,” he said in Tuesday’s statement.
“Her legacy as a pioneer will live on and she will forever be remembered for her courage and good nature.”
Latest Stories
-
Every Ghanaian worker must retire with dignity in pension system – Mahama
17 minutes -
Ejisu NHIA incident shouldn’t escalate to national level – Health Committee Chair
22 minutes -
Ejisu NHIA office lock-up sets dangerous precedent – MP
25 minutes -
Finance Minister confirms start of public sector recruitments despite high wage bill
28 minutes -
Ofoase/Ayirebi NPP mourns fallen police officers, urges road safety
42 minutes -
Kade MP demands accountability over ‘unrealistic revenue targets’ and $240m gold loss
56 minutes -
Fuel tanker explosion at Potsin leaves hundreds stranded on Kasoa-Winneba highway
1 hour -
Rising fuel prices: Damongo MP urges Mahama to hold emergency meeting, provide relief
2 hours -
If gov’t could recruit 20k, why not earlier? – Nitiwul questions security recruitment plan
2 hours -
Adu Boahene’s trial: Witness claims he arranged funds to pre-finance National Security suppliers
2 hours -
Empowering nonprofits article for sustainable impact
2 hours -
Focus must remain on Ukraine despite Iran war, PM says
2 hours -
Top US counterterrorism official resigns over Iran war, urging Trump to ‘reverse course’
2 hours -
World Cup 2026: Current match schedule unchanged – FIFA on Iran’s request for change of host country
2 hours -
New Juaben South MP calls for arrest of NDC youth who locked up Ejisu NHIA office
2 hours
