Five individuals in Vice President Mike Pence's orbit have tested positive for the coronavirus, including his chief of staff Marc Short and political aide Marty Obst.

"Today, Marc Short, Chief of Staff to the Vice President, tested positive for Covid-19, began quarantine and assisting in the contact tracing process," Devin O'Malley, press secretary for the vice president, said in a statement Saturday.

Mike Pence's chief of staff Marc Short, other top aide test positive for COVID-19 https://t.co/pe1PQL7AEK via @Yahoo

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Sunday morning, multiple sources familiar with the matter told ABC News that in addition to an outside political ally of Pence's four of his staffers have tested positive.

One senior level source stressed that the three of the staffers have been quarantining since the middle of this past week.

O'Malley said both Pence and wife Karen Pence tested negative for the virus on Saturday.

Pence has been crisscrossing the country on the campaign trail for weeks. He made visits to Lakeland and Tallahassee, Florida, on Saturday.

On Friday, he spent time in his home state of Indiana, where he voted in person in Indianapolis, before holding rallies in Ohio and Pennsylvania.

He will continue his schedule, O'Malley said, despite the close contact with Short.

"While Vice President Pence is considered a close contact with Mr. Short, in consultation with the White House Medical Unit, the Vice President will maintain his schedule in accordance with the CDC guidelines for essential personnel," he wrote in a statement.

The Centers for Disease Control and Prevention advise essential workers who have been exposed to COVID-19 should take their temperature before work, wear a face mask at all times and social distance "as work duties permit."

Pence is scheduled to hold a rally in Kinston, North Carolina, on Sunday evening.

President Donald Trump, upon disembarking Air Force One at Joint Base Andrews, was asked about Short's positive test.

"I did hear about him just now and I think he's quarantining. I did hear about him," the president said. "He's going to be fine but he's quarantining. Thank you very much."

Short has served as Pence's chief of staff since March 2019.

Obst, a top political aide to the vice president, tested positive last week, multiple sources familiar with the matter told ABC News.

He is an outside adviser and not a government employee.

He was spotted at a fundraiser at Trump Doral attended by both Pence and President Trump on October 15.

While he was traveling with the VP last week, he wasn't in close proximity to him, sources say.