Audio By Carbonatix
If you are a man who has hesitated to get the Covid-19 vaccine due to concerns spread on social media that the vaccine may harm fertility, take heart.
Sperm count and quality did not drop in healthy young men after receiving a first or second dose of the Pfizer or Moderna vaccine, according to a new study published Thursday in JAMA.
"We now have evidence that should reassure you that the risk of immunization compromising your sperm count is extremely low," said Dr. David Cohen, co-medical director of the Institute for Human Reproduction in Chicago, who was not involved in the study. Cohen was the co-author of a systematic review that found the novel coronavirus is not sexually transmitted.
"This is reassuring data which suggests that sperm quality is not significantly altered by receiving two doses of one of the new mRNA vaccines for COVID-19," said Allan Pacey, professor of andrology at the University of Sheffield in the UK, who also was not involved in the study.
"I hope this provides some reassurance to any men who may be concerned about their fertility if they accept one of these types of vaccines," said Pacey, who is also editor-in-chief of the journal Human Fertility.
Small study of young, healthy men
The study used semen samples from 45 men between the ages of 25 and 31, who were pre-screened to make sure they had no fertility issues. Samples were taken before the first shot of an mRNA vaccine, then 70 days after the second dose. Semen was then examined to determine sperm volume, concentration, motility and total sperm count.
"We found no changes in sperm parameters in the young healthy men that we studied who received both doses of mRNA vaccine," said study author Dr. Ranjith Ramasamy, director of male reproductive medicine and surgery at the University of Miami Health System.
The study did not test the Johnson & Johnson or AstraZeneca vaccines, which are not based on mRNA platforms."
However, we think the mechanism of how these vaccines work is all fairly similar despite different genetic material, so based on biology, we don't think there should be anything different with the other two vaccines," Ramasamy said.
Additional larger studies with men of different ages are needed to affirm the study's results, Pacey said.
Covid-19 virus may impact sperm
While the vaccine had no impact on male sperm in the study, the virus itself could be harmful to the male reproductive tract, according to a small study published in January.
Compared to healthy men without Covid-19, the study found a significant increase in inflammation and oxidative stress in sperm cells belonging to men with Covid-19. Their sperm concentration, mobility and shape were also negatively impacted by the virus.
The differences grew with the severity of the sickness, the study found.
It's not surprising that SARS-CoV-2, the virus that causes Covid-19, might impact the male reproductive system, because ACE2 receptors, the "same receptors which the virus uses to gain access to the tissues of the lung, are also found in the testicles," Pacey said.
Pacey has reviewed over a dozen studies published on the topic, and he told CNN in January he had concluded that "any measurable effect of coronavirus on male fertility was probably only slight and temporary."
Medications used to treat Covid-19, fevers, obesity and many other factors can also impact sperm count and quality, so larger studies would need to be done to ensure that it was the virus causing the effect, Pacey said.
"We know that some viruses like Zika or Ebola can remain in the testicles for a long period of time --long after the man has recovered from them. So we need to study men in the longer term to know if this is also the case for Covid-19," he said.
Latest Stories
-
Howe unsure over Guimaraes amid Arsenal interest
11 minutes -
Richarlison scores as Spurs beat Auckland at Eden Park
22 minutes -
CCMG calls for migration governance to be decentralised to district assemblies
25 minutes -
Gittens keen to impress ‘world-class’ Alonso
29 minutes -
Unhappy Tottenham players should leave – De Zerbi
35 minutes -
Deputy A-G dismisses Miracles Aboagye’s claim EOCO never questioned him over GHC55m
37 minutes -
Female referee injured in melee during friendly
42 minutes -
Chiesa happy but wants new chapter at Liverpool
49 minutes -
Glasgow 2026: Nancy Bamfo, Adelaide Djabatey eliminated in women’s 54kg boxing
1 hour -
Ghana’s construction ‘Gross Value Added’ to slow down in 2027, 2028 – Fitch Solutions
2 hours -
42-year-old man jailed 10 years for defiling 7-year-old boy in Wa
3 hours -
T-bills: Government exceeds target by 30%; interest rates decline again
3 hours -
Man jailed 10 years for defiling seven-year-old boy in Wa
3 hours -
Trump paused attacks on Iran to make space for talks, US ambassador says
3 hours -
NSMQ 2026 : Boa Amponsem SHTS makes light work of rivals to reach nationals
4 hours